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CENTRE =
NATIONAL DE LA=20
RECHERCHE SCIENTIFIQUE UNIVERSIT=C3=89 RENNES 1 U.M.R=20 6061 G=C3=89N=C3=89TIQUE ET = D=C3=89VELOPPEMENT |
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| Genetic Study of =
Malignant=20
Histiocytosis in the Bernese Mountain Dog : a collaborative=20 study |
| C. Andr=C3=A9 (CNRS, =
Rennes, France),=20
M. Breen (NCSU, Raleigh, US) E. Ostrander (NIH, Bethesda, = US) |
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| Since we wish to find the genes responsible for =
Malignant=20
Histiocytosis in dogs as quickly as possible, our three =
laboratories have=20
been funded by the AKC-Canine Health Foundation to collaborate on =
this=20
project and more samples are needed.=20
1. If your BMD is over 10 years of age and has never been =
diagnosed=20
with MH : a blood sample is useful to us as a control (it is =
essential=20
that you contact us if your dog is later diagnosed with MH). 1) 5 ml of blood in EDTA (lilac top) tubes (name, breed, sex, =
written=20
on the tube) Please send blood samples at room temperature by rapid delivery =
mail. From Europe, send to: From the US: Dr. Matthew Breen : contact : If your BMD is affected by malignant histiocytosis, fresh = samples of=20 histiocytic sarcoma is needed for Dr. Cheryl London=E2=80=99s = study for developing=20 effective therapeutics for affected dogs. In order to complete = this task,=20 it is necessary for them to receive tumor tissue which has been=20 appropriately preserved so that the RNA can be extracted. (Note = =E2=80=93 all=20 samples must be taken from an animal either at the time of surgery = or=20 immediately post-euthanasia.) Therefore, it will be necessary for = us to=20 send you in advance an RNA stabilizing agent (RNA Later) prior to = sample=20 collection, as well as tubes for collection of samples. If you = think that=20 you may be able to provide tissue for this project, please contact = Dr.=20 Cheryl London at the following address: They desperately need fresh samples for this project, and = greatly=20 appreciate each contribution. |
| Facult=C3=A9 de=20
M=C3=A9decine 2, avenue du Professeur L=C3=A9on Bernard 35043 = RENNES Cedex Tel=20 : 02 23 23 45 09 Fax : 02 23 23 44 78 |